Lipoteichoic Acid 抗体
This anti-Lipoteichoic Acid antibody is a 小鼠 单克隆 antibody detecting Lipoteichoic Acid in ELISA. Suitable for Gram Positive Bacteria.
Quick Overview for Lipoteichoic Acid 抗体 (ABIN7232846)
抗原
See all Lipoteichoic Acid (LTA) 抗体
Lipoteichoic Acid (LTA)
适用
Gram Positive Bacteria
宿主
小鼠
克隆类型
单克隆
标记
This Lipoteichoic Acid antibody is un-conjugated
应用范围
ELISA
克隆位点
15711
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原理
- Anti-Lipoteichoic Acid Mouse Monoclonal Antibody
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特异性
- This antibody reacts with lipoteichoic acid of Staph epidermidis, Hay strain, as well as clinical strains of Staph. epidermidis (types I, II, and III), Staph. aureus strains 5 and 8, Strep. pyogenes, Strep. fecaelis, and Strep. mutans. It does not react with peptido- glycan of Staph. aureus or peptidoglycan- rhamnose, nor does it react with pneumococcal polysaccharides. This antibody does not cross-react with E. coli or H. influenzae type B.
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交叉反应
- Gram Positive Bacteria
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免疫原
- Staphylococcus epidermidis, Hay strain (ATCC #55133).
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亚型
- IgG1
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应用备注
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ELISA: use at 0.1-1.0 μg/mL (optimized for LTA on solid phase).
Opsonization assay: use at 80-160 μg/mL (optimized for Staph. epidermidis, Hay strain). -
限制
- 仅限研究用
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状态
- Liquid
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溶解方式
- Dilute in PBS or medium that is identical to that used in the assay system.
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浓度
- Lot specific
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缓冲液
- PBS, pH 7.4
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储存条件
- -20 °C
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储存方法
- This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze-thaw cycles.
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- Lipoteichoic Acid (LTA)
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别名
- Lipoteichoic acid
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物质类
- Chemical
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背景
- Lipoteichoic acid (LTA) is the major proinflammatory structure present within the cell wall layer of most gram-positive bacteria. It plays an important role in the initiation and progression of bacterial infection, inflammation, and septic shock. LTA induces several cytokines in vivo, and LTA and peptidoglycan (PepG) synergize to cause the induction of nitric oxide formation which can lead to multiple organ failure. Since LTA is also found in the cell walls of non-pathogenic gram-positive bacteria, it has been suggested that the structure of LTA , and its ability to synergize with PepG, determines the ability of a particular bacterium to cause septic shock.
抗原
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