ZNF384 抗体 (N-Term)
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Quick Overview for ZNF384 抗体 (N-Term) (ABIN7218572)
抗原
See all ZNF384 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- ZNF384 Polyclonal Antibody
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特异性
- ZNF384 Polyclonal Antibody detects endogenous levels of ZNF384 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the N-terminal region of human ZNF384
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- ZNF384 (Zinc Finger Protein 384 (ZNF384))
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别名
- ZNF384
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背景
- Rabbit Anti-ZNF384 Polyclonal Antibody,ZNF384, CAGH1, CIZ, NMP4, TNRC1, Zinc finger protein 384, CAG repeat protein 1, CAS-interacting zinc finger protein, Nuclear matrix transcription factor 4, Nuclear matrix protein 4, Trinucleotide repeat-containing gene 1 protein,ZNF384 encodes a C2H2-type zinc finger protein, which may function as a transcription factor. This gene also contains long CAG trinucleotide repeats that encode consecutive glutamine residues. The protein appears to bind and regulate the promoters of the extracellular matrix genes MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Alternative splicing results in multiple transcript variants. Recurrent rearrangements of this gene with the Ewing's sarcoma gene, EWSR1 on chromosome 22, or with the TAF15 gene on chromosome 17, or with the TCF3 (E2A) gene on chromosome 19, have been observed in acute leukemia. A related pseudogene has been identified on chromosome 7.,Zinc finger protein 384
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分子量
- observerd band 64kDa
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基因ID
- 171017
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UniProt
- Q8TF68
抗原
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