XDH 抗体
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北京 101111
Quick Overview for XDH 抗体 (ABIN7232182)
抗原
See all XDH 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- XDH Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of XDH protein
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human XDH protein
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- XDH (Xanthine Dehydrogenase (XDH))
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别名
- XDH
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背景
- Rabbit Anti-XDH Polyclonal Antibody,Xanthine dehydrogenase/oxidase, Xanthine oxidoreductase, XOR,XDH (Xanthine Dehydrogenase) is a Protein Coding gene. Diseases associated with XDH include Xanthinuria, Type I and Xanthinuria. Among its related pathways are Doxorubicin Pathway, Pharmacokinetics and Metabolism. XDH belongs to the group of molybdenum-containing hydroxylases involved in the oxidative metabolism of purines. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. XDH can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic modification. Defects in XDH cause xanthinuria, may contribute to adult respiratory stress syndrome, and may potentiate influenza infection through an oxygen metabolite-dependent mechanism.,XDH
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分子量
- observerd band 146kDa
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基因ID
- 7498
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UniProt
- P47989
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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