VN2R1P 抗体 (AA 350-430)
This 兔 多克隆 anti-VN2R1P antibody specifically detects VN2R1P in ELISA, WB 和 IF. The antibody is reactive with 人 samples.
产品编号 ABIN7221684
发货至:
中国
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中国
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Quick Overview for VN2R1P 抗体 (AA 350-430) (ABIN7221684)
抗原
VN2R1P
(Vomeronasal 2 Receptor 1 Pseudogene (VN2R1P))
适用
人
宿主
兔
克隆类型
多克隆
标记
This VN2R1P antibody is un-conjugated
应用范围
ELISA, Western Blotting (WB), Immunofluorescence (IF)
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抗原表位
- AA 350-430
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原理
- VN2R1P Polyclonal Antibody
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特异性
- VN2R1P Polyclonal Antibody detects endogenous levels of VN2R1P protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human VN2R1P at AA range: 350-430
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- VN2R1P (Vomeronasal 2 Receptor 1 Pseudogene (VN2R1P))
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别名
- VN2R1P
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背景
- Rabbit Anti-VN2R1P Polyclonal Antibody,The CARL-1 monoclonal antibody reacts with human TWEAK, a type II transmembrane TNF superfamily member with high identity to TNF in its extracellular portion. TWEAK transcript is expressed broadly in many adult and fetal tissues, however, the staining of human peripheral blood mononuclear cells with monoclonal antibodies shows a more restricted pattern. While freshly isolated PBMCs do not express detectable levels of TWEAK on their surface, IFN-gamma-stimulated blood monocytes rapidly upregulate TWEAK surface expression. TWEAK is expressed as membrane bound and secreted forms. Interaction of TWEAK with its counter-receptor promotes secretion of IL-8, activation of NF-kappaB, proliferation of endothelial cells, and apoptosis in a number of human cell lines. Initially, DR3 was thought to be a receptor for TWEAK, but further studies have shown that TWEAK could induce apoptosis via receptors distinct from DR3. While TWEAK exhibits overlapping signaling functions to TNF, it is generally less effective in inducing apoptosis, giving rise to its name, TNF-like weak inducer of apoptosis. For detection of human TWEAK by sandwich ELISA, a combination of purified CARL-2 for capture and biotinylated CARL-1 for detection is recommended.,Putative calcium-sensing receptor-like 1
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分子量
- observerd band 83kDa
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基因ID
- 344760
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UniProt
- Q8NGV9
抗原
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