Uromodulin 抗体 (Internal Region)
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北京 101111
Quick Overview for Uromodulin 抗体 (Internal Region) (ABIN7224866)
抗原
See all Uromodulin (UMOD) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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原理
- THP Polyclonal Antibody
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特异性
- THP Polyclonal Antibody detects endogenous levels of THP protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human THP
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亚型
- IgG
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anti-Uromodulin (UMOD) (AA 351-450) antibody
UMOD 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Uromodulin (UMOD) (AA 25-120) antibodyUMOD 适用: 人 WB, IP, ELISA 宿主: 小鼠 Monoclonal 3F10 unconjugated
anti-Uromodulin (UMOD) (AA 32-151) antibodyUMOD 适用: 犬 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Uromodulin (UMOD) (AA 1-611) antibodyUMOD 适用: 人 WB, IHC (p), IF 宿主: 小鼠 Polyclonal unconjugated
anti-Uromodulin (UMOD) (AA 1-611) antibodyUMOD 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Uromodulin (UMOD) (AA 334-589) antibodyUMOD 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Uromodulin (UMOD) (C-Term) antibodyUMOD 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Uromodulin (UMOD) antibodyUMOD 适用: 人, 犬 IHC, IHC (p), IF, IHC (fro) 宿主: 小鼠 Monoclonal 10-32 unconjugated
anti-Uromodulin (UMOD) (AA 335-590) antibodyUMOD 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Uromodulin (UMOD) (AA 30-150) antibodyUMOD 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Uromodulin (UMOD)
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别名
- THP
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背景
- Rabbit Anti-THP Polyclonal Antibody,UMOD, Uromodulin, Tamm-Horsfall urinary glycoprotein, THP,The protein encoded by UMOD (uromodulin) is the most abundant protein in mammalian urine under physiological conditions. Its excretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl phosphatidylinosital-anchored counterpart that is situated on the luminal cell surface of the loop of Henle. This protein may act as a constitutive inhibitor of calcium crystallization in renal fluids. Excretion of this protein in urine may provide defense against urinary tract infections caused by uropathogenic bacteria. Defects in UMOD are associated with the renal disorders medullary cystic kidney disease-2 (MCKD2), glomerulocystic kidney disease with hyperuricemia and isosthenuria (GCKDHI), and familial juvenile hyperuricemic nephropathy (FJHN). Alternative splicing of UMOD results in multiple transcript variants.,Uromodulin
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分子量
- observerd band 70kDa
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基因ID
- 7369
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UniProt
- P07911
抗原
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