UBE2O 抗体
Quick Overview for UBE2O 抗体 (ABIN7232000)
抗原
See all UBE2O 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- UBE2O Polyclonal Antibody
-
特异性
- The antibody detects endogenous levels of UBE2O protein
-
纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
-
免疫原
- Synthesized peptide derived from part region of human UBE2O protein
-
亚型
- IgG
-
-
anti-Ubiquitin-Conjugating Enzyme E2O (UBE2O) (AA 1073-1292) antibody
UBE2O 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2O (UBE2O) (AA 361-470) antibodyUBE2O 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2C10 unconjugated
anti-Ubiquitin-Conjugating Enzyme E2O (UBE2O) (AA 10-277) antibodyUBE2O 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2O (UBE2O) (AA 1-741) antibodyUBE2O 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2O (UBE2O) (AA 1079-1128) antibodyUBE2O 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 猴, Pig, Bat, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
-
说明
-
Primary Antibody
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
-
- UBE2O (Ubiquitin-Conjugating Enzyme E2O (UBE2O))
-
别名
- UBE2O
-
背景
- Rabbit Anti-UBE2O Polyclonal Antibody,(E3-independent) E2 ubiquitin-conjugating enzyme, E2/E3 hybrid ubiquitin-protein ligase UBE2O, Ubiquitin carrier protein O, Ubiquitin-conjugating enzyme E2 O, Ubiquitin-conjugating enzyme E2 of 230 kDa, Ubiquitin-conjugating enzyme E2-230K, Ubiquitin-protein ligase O,E2/E3 hybrid ubiquitin-protein ligase that displays both E2 and E3 ligase activities and mediates monoubiquitination of target proteins. Negatively regulates TRAF6-mediated NF-kappa-B activation independently of its E2 activity. Acts as a positive regulator of BMP7 signaling by mediating monoubiquitination of SMAD6, thereby regulating adipogenesis. Mediates monoubiquitination at different sites of the nuclear localization signal (NLS) of BAP1, leading to cytoplasmic retention of BAP1. Also able to monoubiquitinate the NLS of other chromatin-associated proteins, such as INO80 and CXXC1, affecting their subcellular location. Acts as a regulator of retrograde transport by assisting the TRIM27: mAGEL2 E3 ubiquitin ligase complex to mediate Lys-63-linked ubiquitination of WASHC1, leading to promote endosomal F-actin assembly.,UBE2O
-
分子量
- observerd band 142kDa
-
基因ID
- 63893
-
UniProt
- Q9C0C9
抗原
-
