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UBE2D3 抗体

The 兔 多克隆 anti-UBE2D3 antibody is suitable to detect UBE2D3 in samples from 人, 小鼠 和 大鼠. It has been validated for WB 和 ELISA.
产品编号 ABIN7231980
发货至: 中国
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Quick Overview for UBE2D3 抗体 (ABIN7231980)

抗原

See all UBE2D3 抗体
UBE2D3 (Ubiquitin-Conjugating Enzyme E2D 3 (UBE2D3))

适用

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人, 小鼠, 大鼠

宿主

  • 43
  • 1

克隆类型

  • 32
  • 12
多克隆

标记

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This UBE2D3 antibody is un-conjugated

应用范围

  • 32
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Western Blotting (WB), ELISA
  • 原理

    Rabbit Anti-UB2D3 Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of UB2D3 protein

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from part region of human UB2D3 protein

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    UBE2D3 (Ubiquitin-Conjugating Enzyme E2D 3 (UBE2D3))

    别名

    UB2D3

    背景

    Ubiquitin-conjugating enzyme E2 D3, E2 ubiquitin-conjugating enzyme D3, Ubiquitin carrier protein D3, Ubiquitin-conjugating enzyme E2-17 kDa 3, Ubiquitin-protein ligase D3UBE2D3 (Ubiquitin Conjugating Enzyme E2 D3) is a Protein Coding gene. Diseases associated with UBE2D3 include Retinitis Pigmentosa 42. Among its related pathways are CDK-mediated phosphorylation and removal of Cdc6 and Protein processing in endoplasmic reticulum. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2D3 encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase.

    分子量

    16kD

    基因ID

    7323

    UniProt

    P61077

    途径

    Activation of Innate immune Response, Toll-Like Receptors Cascades
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