USP13 抗体 (AA 780-860)
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北京 101111
Quick Overview for USP13 抗体 (AA 780-860) (ABIN7225734)
抗原
See all USP13 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 780-860
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原理
- USP13 Polyclonal Antibody
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特异性
- USP13 Polyclonal Antibody detects endogenous levels of USP13 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the C-terminal region of human USP13 at AA range: 780-860
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亚型
- IgG
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anti-Ubiquitin Specific Peptidase 13 (Isopeptidase T-3) (USP13) (C-Term) antibody
USP13 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 13 (Isopeptidase T-3) (USP13) antibodyUSP13 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 13 (Isopeptidase T-3) (USP13) (AA 500-550) antibodyUSP13 适用: 人, 小鼠, 犬, 马, Cow, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 13 (Isopeptidase T-3) (USP13) antibodyUSP13 适用: 人, 犬, 猴 WB, IHC, IP 宿主: 小鼠 Monoclonal 4G11 unconjugated
anti-Ubiquitin Specific Peptidase 13 (Isopeptidase T-3) (USP13) (AA 387-420) antibodyUSP13 适用: 斑马鱼 WB 宿主: 兔 Polyclonal RB52034 unconjugated
anti-Ubiquitin Specific Peptidase 13 (Isopeptidase T-3) (USP13) antibodyUSP13 适用: 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 13 (Isopeptidase T-3) (USP13) (AA 1-863) antibodyUSP13 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 13 (Isopeptidase T-3) (USP13) (AA 161-210) antibodyUSP13 适用: 人, 小鼠, 大鼠, 犬, 马, Cow, 豚鼠, 兔, 猴, Pig, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 13 (Isopeptidase T-3) (USP13) (AA 389-419) antibodyUSP13 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB4304 unconjugated
anti-Ubiquitin Specific Peptidase 13 (Isopeptidase T-3) (USP13) (AA 811-860) antibodyUSP13 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- USP13 (Ubiquitin Specific Peptidase 13 (Isopeptidase T-3) (USP13))
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别名
- USP13
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背景
- Rabbit Anti-USP13 Polyclonal Antibody,USP13, ISOT3, Ubiquitin carboxyl-terminal hydrolase 13, Deubiquitinating enzyme 13, Isopeptidase T-3, ISOT-3, Ubiquitin thioesterase 13, Ubiquitin-specific-processing protease 13,Ubiquitinating enzymes (UBEs) catalyze protein ubiquitination, a reversible process countered by deubiquitinating enzyme (DUB) action. Five DUB subfamilies are recognized, including the USP, UCH, OTU, MJD, and JAMM enzymes. Ubiquitin carboxyl-terminal hydrolase 13 (USP13, isopeptidase T-3) contains four ubiquitin-associated/translation elongation factor EF1B, amino terminal (UBA) domains and one ubiquitin-specific processing protease (UBP) domain. The UBP domain of USP13 contains a catalytic site, a zinc finger domain, and two UBA domains. Similar to other USP family members, USP13 contains cysteines and histidines that are likely involved in its catalytic mechanism. Studies show that USP13 plays a critical role in autophagy through the deubiquitination of target proteins such as BECN1 and USP10. Research also suggests that USP13 is implicated in the pathogenesis of melanoma through its ability to regulate the ubiquitination status of MITF.,Ubiquitin carboxyl-terminal hydrolase 13
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分子量
- observerd band 97kDa
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基因ID
- 8975
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UniProt
- Q92995
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途径
- SARS-CoV-2 Protein Interactome
抗原
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