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USP11 抗体 (Internal Region)

This anti-USP11 antibody is a 兔 多克隆 antibody detecting USP11 in WB 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7218842
发货至: 中国

Quick Overview for USP11 抗体 (Internal Region) (ABIN7218842)

抗原

See all USP11 抗体
USP11 (Ubiquitin Specific Peptidase 11 (USP11))

适用

  • 58
  • 21
  • 21
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 50
  • 7
  • 1

克隆类型

  • 32
  • 26
多克隆

标记

  • 30
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This USP11 antibody is un-conjugated

应用范围

  • 43
  • 17
  • 14
  • 14
  • 13
  • 12
  • 12
  • 3
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 11
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Internal Region

    原理

    USP11 Polyclonal Antibody

    特异性

    USP11 Polyclonal Antibody detects endogenous levels of USP11 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the Internal region of human USP11

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    USP11 (Ubiquitin Specific Peptidase 11 (USP11))

    别名

    USP11

    背景

    Rabbit Anti-USP11 Polyclonal Antibody,USP11, UHX1, Ubiquitin carboxyl-terminal hydrolase 11, Deubiquitinating enzyme 11, Ubiquitin thioesterase 11, Ubiquitin-specific-processing protease 11,USP11 (Ubiquitin Specific Peptidase 11) is a Protein Coding gene. Among its related pathways are Transport to the Golgi and subsequent modification and Chaperonin-mediated protein folding. GO annotations related to this gene include cysteine-type endopeptidase activity and thiol-dependent ubiquitinyl hydrolase activity. An important paralog of this gene is USP4. rotease that can remove conjugated ubiquitin from target proteins and polyubiquitin chains (PubMed: 12084015, PubMed: 15314155, PubMed: 17897950, PubMed: 19874889, PubMed: 20233726, PubMed: 24724799). Inhibits the degradation of target proteins by the proteasome (PubMed: 12084015). Cleaves preferentially Lys-6 and Lys-63-linked ubiquitin chains. Has lower activity with Lys-11 and Lys-33-linked ubiquitin chains, and extremely low activity with Lys-27, Lys-29 and Lys-48-linked ubiquitin chains (in vitro) (PubMed: 24724799). Plays a role in the regulation of pathways leading to NF-kappa-B activation (PubMed: 17897950, PubMed: 19874889). Plays a role in the regulation of DNA repair after double-stranded DNA breaks (PubMed: 15314155, PubMed: 20233726).,Ubiquitin carboxyl-terminal hydrolase 11

    分子量

    observerd band 105kDa

    UniProt

    P51784
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