TNK2 抗体
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北京 101111
Quick Overview for TNK2 抗体 (ABIN7218910)
抗原
See all TNK2 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- ACK Polyclonal Antibody
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特异性
- ACK Polyclonal Antibody detects endogenous levels of ACK protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human ACK around the non-phosphorylation site of Y284
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- TNK2 (tyrosine Kinase, Non-Receptor, 2 (TNK2))
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别名
- ACK
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背景
- Rabbit Anti-ACK Polyclonal Antibody,TNK2, ACK1, Activated CDC42 kinase 1, ACK-1, Tyrosine kinase non-receptor protein 2,TNK2 encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The tyrosine kinase non receptor 2 may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc43Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined.,Activated CDC42 kinase 1
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基因ID
- 10188
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UniProt
- Q07912
抗原
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