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TNK2 抗体 (pTyr284)

This 兔 多克隆 anti-TNK2 antibody specifically detects TNK2 in WB, ELISA, IF 和 IHC (p). The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN7218908
发货至: 中国
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Quick Overview for TNK2 抗体 (pTyr284) (ABIN7218908)

抗原

See all TNK2 抗体
TNK2 (tyrosine Kinase, Non-Receptor, 2 (TNK2))

适用

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人, 小鼠

宿主

  • 115
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克隆类型

  • 117
  • 1
多克隆

标记

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This TNK2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    pTyr284

    原理

    ACK (phospho Tyr284) Polyclonal Antibody

    特异性

    Phospho-ACK (Y284) Polyclonal Antibody detects endogenous levels of ACK protein only when phosphorylated at Y284.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from human ACK Phospho-Tyr284

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    TNK2 (tyrosine Kinase, Non-Receptor, 2 (TNK2))

    别名

    ACK

    背景

    Rabbit Anti-ACK (phospho Tyr284) Polyclonal Antibody,TNK2, ACK1, Activated CDC42 kinase 1, ACK-1, Tyrosine kinase non-receptor protein 2,TNK2 encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The tyrosine kinase non receptor 2 may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined.,Activated CDC42 kinase 1

    基因ID

    10188

    UniProt

    Q07912
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