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TSG101 抗体 (AA 250-330)

This 兔 多克隆 anti-TSG101 antibody specifically detects TSG101 in WB, ELISA, IF 和 IHC (p). The antibody is reactive with 人, 小鼠, 大鼠 和 猴 samples.
产品编号 ABIN7224820
发货至: 中国
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Quick Overview for TSG101 抗体 (AA 250-330) (ABIN7224820)

抗原

See all TSG101 抗体
TSG101 (Tumor Susceptibility Gene 101 (TSG101))

适用

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人, 小鼠, 大鼠, 猴

宿主

  • 76
  • 19
  • 1

克隆类型

  • 55
  • 41
多克隆

标记

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This TSG101 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 9
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    • 4
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    AA 250-330

    原理

    Tsg 101 Polyclonal Antibody

    特异性

    Tsg 101 Polyclonal Antibody detects endogenous levels of Tsg 101 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the C-terminal region of human Tsg 101 at AA range: 250-330

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    TSG101 (Tumor Susceptibility Gene 101 (TSG101))

    别名

    Tsg 101

    背景

    Rabbit Anti-Tsg 101 Polyclonal Antibody,TSG101, Tumor susceptibility gene 101 protein, ESCRT-I complex subunit TSG101,The protein encoded by TSG101 (tumor susceptibility 101) belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in TSG101 occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression.,Tumor susceptibility gene 101 protein

    分子量

    observerd band 44kDa

    基因ID

    7251

    UniProt

    Q99816
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