TSG101 抗体 (AA 250-330)
Our Local Distributor
北京 101111
Quick Overview for TSG101 抗体 (AA 250-330) (ABIN7224820)
抗原
See all TSG101 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 250-330
-
原理
- Tsg 101 Polyclonal Antibody
-
特异性
- Tsg 101 Polyclonal Antibody detects endogenous levels of Tsg 101 protein.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
-
免疫原
- Synthesized peptide derived from the C-terminal region of human Tsg 101 at AA range: 250-330
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.
-
说明
-
Primary Antibody
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
-
- TSG101 (Tumor Susceptibility Gene 101 (TSG101))
-
别名
- Tsg 101
-
背景
- Rabbit Anti-Tsg 101 Polyclonal Antibody,TSG101, Tumor susceptibility gene 101 protein, ESCRT-I complex subunit TSG101,The protein encoded by TSG101 (tumor susceptibility 101) belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in TSG101 occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression.,Tumor susceptibility gene 101 protein
-
分子量
- observerd band 44kDa
-
基因ID
- 7251
-
UniProt
- Q99816
抗原
-