TUBGCP4 抗体 (AA 160-240)
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Quick Overview for TUBGCP4 抗体 (AA 160-240) (ABIN7215030)
抗原
See all TUBGCP4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 160-240
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原理
- GCP4 Polyclonal Antibody
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特异性
- GCP4 Polyclonal Antibody detects endogenous levels of GCP4 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human GCP4 at AA range: 160-240
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- TUBGCP4 (Tubulin, gamma Complex Associated Protein 4 (TUBGCP4))
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别名
- GCP4
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背景
- Rabbit Anti-GCP4 Polyclonal Antibody,TUBGCP4, 76P, GCP4, Gamma-tubulin complex component 4, GCP-4, hGCP4, Gamma-ring complex protein 76 kDa, h76p, hGrip76,TUBGCP4 encodes a component of the gamma-tubulin ring complex, gamma-tubulin complex component 4, which is required for microtubule nucleation. In mammalian cells, the protein localizes to centrosomes in association with gamma-tubulin. Crystal structure analysis revealed a structure composed of five helical bundles arranged around conserved hydrophobic cores. An exposed surface area located in the C-terminal domain is essential and sufficient for direct binding to gamma-tubulin. Mutations in this gene that alter microtubule organization are associated with microcephaly and chorioretinopathy. Alternative splicing results in multiple transcript variants.,Gamma-tubulin complex component 4
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分子量
- observerd band 76kDa
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基因ID
- 27229
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UniProt
- Q9UGJ1
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途径
- M Phase
抗原
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