TPSD1 抗体 (AA 51-100)
Quick Overview for TPSD1 抗体 (AA 51-100) (ABIN7226870)
抗原
See all TPSD1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 51-100
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原理
- Tryptase-3 Polyclonal Antibody
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特异性
- Tryptase-3 Polyclonal Antibody detects endogenous levels of Tryptase-3.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from Tryptase-3 at AA range: 51-100
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- TPSD1 (Tryptase delta 1 (TPSD1))
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别名
- Tryptase-3
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背景
- Rabbit Anti-Tryptase-3 Polyclonal Antibody,Tryptase delta , Delta-tryptase, H mMCP-3-like tryptase III, Mast cell mMCP-7-like, Tryptase-3,Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. Although TPSD1 (tryptase delta 1) may be an exception, most of the tryptase genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. TPSD1 was once considered to be a pseudogene, although it is now believed to be a functional gene that encodes a protein.,Tryptase-3
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分子量
- observerd band 26kDa
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基因ID
- 23430
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UniProt
- Q9BZJ3
抗原
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