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TNNI2 抗体 (pSer22)

The 兔 多克隆 anti-TNNI2 antibody is suitable to detect TNNI2 in samples from 小鼠 和 大鼠. It has been validated for WB, IHC, ELISA 和 IF.
产品编号 ABIN7218820
发货至: 中国
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Quick Overview for TNNI2 抗体 (pSer22) (ABIN7218820)

抗原

See all TNNI2 抗体
TNNI2 (Fast Skeletal Troponin I (TNNI2))

适用

  • 54
  • 37
  • 28
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
小鼠, 大鼠

宿主

  • 46
  • 17
  • 2

克隆类型

  • 35
  • 30
多克隆

标记

  • 41
  • 6
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
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This TNNI2 antibody is un-conjugated

应用范围

  • 54
  • 25
  • 22
  • 17
  • 10
  • 6
  • 3
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 10
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer22

    原理

    Rabbit Anti-Troponin I-C (phospho Ser22/S23) Polyclonal Antibody

    特异性

    Phospho-Troponin I-C (S22/S23) Polyclonal Antibody detects endogenous levels of Troponin I-C protein only when phosphorylated at S22/S23.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from human Troponin I-C Phospho-Ser22/S23

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    TNNI2 (Fast Skeletal Troponin I (TNNI2))

    别名

    Troponin I-C

    背景

    TNNI3, TNNC1, Troponin I, cardiac muscle, Cardiac troponin ITroponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit, blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: tnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).

    分子量

    28kD

    基因ID

    7137

    UniProt

    P19429
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