TNNI2 抗体
Our Local Distributor
北京 101111
Quick Overview for TNNI2 抗体 (ABIN7217390)
抗原
See all TNNI2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- Troponin I-C Polyclonal Antibody
-
特异性
- Troponin I-C Polyclonal Antibody detects endogenous levels of Troponin I-C protein.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
-
免疫原
- Synthesized peptide derived from human Troponin I-C around the non-phosphorylation site of S43
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.
-
说明
-
Primary Antibody
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
-
- TNNI2 (Fast Skeletal Troponin I (TNNI2))
-
别名
- Troponin I-C
-
背景
- Rabbit Anti-Troponin I-C Polyclonal Antibody,TNNI3, TNNC1, Troponin I, cardiac muscle, Cardiac troponin I,Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit, blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: tnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. TNNI3 encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).,Troponin I cardiac muscle
-
分子量
- observerd band 26kDa
-
基因ID
- 7137
-
UniProt
- P19429
抗原
-