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Transportin 1 抗体

This 兔 多克隆 anti-Transportin 1 antibody specifically detects Transportin 1 in WB 和 ELISA. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN7231862
发货至: 中国
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Quick Overview for Transportin 1 抗体 (ABIN7231862)

抗原

See all Transportin 1 (TNPO1) 抗体
Transportin 1 (TNPO1)

适用

  • 40
  • 27
  • 17
  • 1
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 40
  • 4

克隆类型

  • 41
  • 3
多克隆

标记

  • 19
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Transportin 1 antibody is un-conjugated

应用范围

  • 36
  • 15
  • 13
  • 13
  • 10
  • 7
  • 6
  • 6
  • 3
  • 1
Western Blotting (WB), ELISA
  • 原理

    TNPO1 Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of TNPO1 protein

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

    免疫原

    Synthesized peptide derived from part region of human TNPO1 protein

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    Transportin 1 (TNPO1)

    别名

    TNPO1

    背景

    Rabbit Anti-TNPO1 Polyclonal Antibody,Transportin-1, Importin beta-2, Karyopherin beta-2, M9 region interaction protein, MIP,TNPO1 (Transportin 1) is a Protein Coding gene. Diseases associated with TNPO1 include Hiv-1 and Dementia, Frontotemporal. Among its related pathways are Development_TGF-beta receptor signaling and CDK-mediated phosphorylation and removal of Cdc6. TNPO1 encodes the beta subunit of the karyopherin receptor complex which interacts with nuclear localization signals to target nuclear proteins to the nucleus. The karyopherin receptor complex is a heterodimer of an alpha subunit which recognizes the nuclear localization signal and a beta subunit which docks the complex at nucleoporins. Alternate splicing of TNPO1 results in two transcript variants encoding different proteins.,TNPO1

    分子量

    observerd band 98kDa

    基因ID

    3842

    UniProt

    Q92973

    途径

    PI3K-Akt Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Cellular Glucan Metabolic Process, Protein targeting to Nucleus, CXCR4-mediated Signaling Events
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