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TMEM30A 抗体 (AA 110-190)

This 兔 多克隆 anti-TMEM30A antibody specifically detects TMEM30A in WB 和 ELISA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7227628
发货至: 中国
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Quick Overview for TMEM30A 抗体 (AA 110-190) (ABIN7227628)

抗原

See all TMEM30A 抗体
TMEM30A (Transmembrane Protein 30A (TMEM30A))

适用

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人, 小鼠, 大鼠

宿主

  • 20
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克隆类型

  • 20
  • 1
多克隆

标记

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This TMEM30A antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

    • 15
    • 1
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    AA 110-190

    原理

    CC50A Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of CC50A protein

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

    免疫原

    Synthesized peptide derived from part region of human CC50A protein at AA range: 110-190

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    TMEM30A (Transmembrane Protein 30A (TMEM30A))

    别名

    CC50A

    背景

    Rabbit Anti-CC50A Polyclonal Antibody,Cell cycle control protein 50A, P4-ATPase flippase complex beta subunit TMEM30A, Transmembrane protein 30A,Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. The beta subunit may assist in binding of the phospholipid substrate. Required for the proper folding, assembly and ER to Golgi exit of the ATP8A2: tMEM30A flippase complex. ATP8A2: tMEM30A may be involved in regulation of neurite outgrowth, and, reconstituted to liposomes, predomiminantly transports phosphatidylserine (PS) and to a lesser extent phosphatidylethanolamine (PE). The ATP8A1: TMEM30A flippase complex seems to play a role in regulation of cell migration probably involving flippase-mediated translocation of phosphatidylethanolamine (PE) at the plasma membrane. Required for the formation of the ATP8A2, ATP8B1 and ATP8B2 P-type ATPAse intermediate phosphoenzymes. Involved in uptake of platelet-activating factor (PAF), synthetic drug alkylphospholipid edelfosine, and, probably in association with ATP8B1, of perifosine. Also mediate the export of alpha subunits ATP8A1, ATP8B1, ATP8B2, ATP8B4, ATP10A, ATP10B, ATP10D, ATP11A, ATP11B and ATP11C from the ER to other membrane localizations.,CC50A

    分子量

    observerd band 39kDa

    基因ID

    55754

    UniProt

    Q9NV96
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