TMPRSS3 抗体 (AA 380-460)
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Quick Overview for TMPRSS3 抗体 (AA 380-460) (ABIN7217340)
抗原
See all TMPRSS3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 380-460
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原理
- TMPRSS3 Polyclonal Antibody
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特异性
- TMPRSS3 Polyclonal Antibody detects endogenous levels of TMPRSS3 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the C-terminal region of human TMPRSS3 at AA range: 380-460
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- TMPRSS3 (Transmembrane Protease, Serine 3 (TMPRSS3))
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别名
- TMPRSS3
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背景
- Rabbit Anti-TMPRSS3 Polyclonal Antibody,TMPRSS3, ECHOS1, TADG12, Transmembrane protease serine 3, Serine protease TADG-12, Tumor-associated differentially-expressed gene 12 protein,TMPRSS3 encodes transmembrane protease serine 3 that belongs to the serine protease family. The transmembrane protease serine 3 contains a serine protease domain, a transmembrane domain, an LDL receptor-like domain, and a scavenger receptor cysteine-rich domain. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. TMPRSS3 was identified by its association with both congenital and childhood onset autosomal recessive deafness. This gene is expressed in fetal cochlea and many other tissues, and is thought to be involved in the development and maintenance of the inner ear or the contents of the perilymph and endolymph. This gene was also identified as a tumor-associated gene that is overexpressed in ovarian tumors. Alternatively spliced transcript variants have been described.,Transmembrane protease serine 3
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分子量
- observerd band 49kDa
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基因ID
- 64699
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UniProt
- P57727
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途径
- Sensory Perception of Sound
抗原
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