TGFBR1 抗体
Quick Overview for TGFBR1 抗体 (ABIN7217298)
抗原
See all TGFBR1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- TGFβ RI Polyclonal Antibody
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特异性
- TGFβ RI Polyclonal Antibody detects endogenous levels of TGFβ RI protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human TGFbeta RI around the non-phosphorylation site of S165
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- TGFBR1 (Transforming Growth Factor, beta Receptor 1 (TGFBR1))
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别名
- TGFbeta RI
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背景
- Rabbit Anti-TGFβ RI Polyclonal Antibody,TGFBR1, ALK5, SKR4, TGF-beta receptor type-1, TGFR-1, Activin A receptor type II-like protein kinase of 53kD, Activin receptor-like kinase 5, ALK-5, ALK5, Serine/threonine-protein kinase receptor R4, SKR4, TGF-beta type I receptor, Transfor,TGF-beta receptor type-1 encoded by TGFBR1 forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The TGF-beta receptor type-1 is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene.,TGF-beta receptor type-1
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分子量
- observerd band 56kDa
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基因ID
- 7046
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UniProt
- P36897
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途径
- Growth Factor Binding
抗原
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