NFE4 抗体 (acLys43)
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Quick Overview for NFE4 抗体 (acLys43) (ABIN7212636)
抗原
See all NFE4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- acLys43
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原理
- NF-E4 (Acetyl Lys43) Polyclonal Antibody
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特异性
- Acetyl-NF-E4 (K43) Polyclonal AntibodySynthesized peptide derived from the human NF-E4 around the acetylation site of K43.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the human NF-E4 around the acetylation site of K43
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- NFE4 (Transcription Factor NF-E4 (NFE4))
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别名
- NF-E4
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背景
- Rabbit Anti-NF-E4 (Acetyl Lys43) Polyclonal Antibody,NFE4, Transcription factor NF-E4,The erythroid-specific protein encoded by NFE4, and the ubiquitous transcription factor CP2, form the stage selector protein(SSP) complex, which is involved in preferential expression of the gamma-globin genes in fetal erythroid cells. Alternate use of an in-frame upstream non-AUG(CUG) translation initiation codon, and a downstream AUG codon, results in two isoforms. While the long isoform(22 kDa) acts as an activator, the short isoform(14 kDa) has been shown to repress gamma-globin gene expression. NFE4 is located in an intron of the FBXL13 gene on the opposite strand.,Transcription factor NF-E4
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分子量
- observerd band 19kDa
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基因ID
- 58160
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UniProt
- Q86UQ8
抗原
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