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MAFK 抗体

This anti-MAFK antibody is a 兔 多克隆 antibody detecting MAFK in WB 和 ELISA. Suitable for 人 和 小鼠.
产品编号 ABIN7229508
发货至: 中国

Quick Overview for MAFK 抗体 (ABIN7229508)

抗原

See all MAFK 抗体
MAFK (Transcription Factor MafK (MAFK))

适用

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人, 小鼠

宿主

  • 23
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克隆类型

  • 23
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多克隆

标记

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This MAFK antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 原理

    MAFK Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of MAFK protein

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

    免疫原

    Synthesized peptide derived from part region of human MAFK protein

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    MAFK (Transcription Factor MafK (MAFK))

    别名

    MAFK

    背景

    Rabbit Anti-MAFK Polyclonal Antibody,Transcription factor MafK, Erythroid transcription factor NF-E2 p18 subunit,The developmentally regulated expression of the globin genes depends on upstream regulatory elements termed locus control regions (LCRs). LCRs are associated with powerful enhancer activity that is mediated by the transcription factor NFE2 (nuclear factor erythroid-2). NFE2 recognition sites are also present in the gene promoters of 2 heme biosynthetic enzymes, porphobilinogen deaminase (PBGD, MIM 609806) and ferrochelatase (FECH, MIM 612386). NFE2 DNA-binding activity consists of a heterodimer containing an 18-kD Maf protein (MafF, MafG (MIM 602020), or MafK) and p45 (MIM 601490). Both subunits are members of the activator protein-1 superfamily of basic leucine zipper (bZIP) proteins (see MIM 165160). Maf homodimers suppress transcription at NFE2 sites. MAFK (MAF BZIP Transcription Factor K) is a Protein Coding gene. Diseases associated with MAFK include Fibrosarcoma. Among its related pathways are Response to elevated platelet cytosolic Ca2+ and Factors involved in megakaryocyte development and platelet production.,MAFK

    分子量

    observerd band 17kDa

    基因ID

    7975

    UniProt

    O60675
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