TNIP3 抗体 (AA 40-120)
Our Local Distributor
北京 101111
Quick Overview for TNIP3 抗体 (AA 40-120) (ABIN7231850)
抗原
See all TNIP3 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 40-120
-
原理
- Rabbit Anti-TNIP3 Polyclonal Antibody
-
特异性
- The antibody detects endogenous levels of TNIP3 protein
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
免疫原
- Synthesized peptide derived from part region of human TNIP3 protein at AA range: 40-120
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
有效期
- 12 months
-
-
- TNIP3 (TNFAIP3 Interacting Protein 3 (TNIP3))
-
别名
- TNIP3
-
背景
- TNFAIP3-interacting protein 3, A20-binding inhibitor of NF-kappa-B activation 3, ABIN-3, Listeria-induced gene proteinTNIP3 (TNFAIP3 Interacting Protein 3) is a Protein Coding gene. Among its related pathways are Ovarian tumor domain proteases and Immune response IL-23 signaling pathway. Binds to zinc finger protein TNFAIP3 and inhibits NF-kappa-B activation induced by tumor necrosis factor, Toll-like receptor 4 (TLR4), interleukin-1 and 12-O-tetradecanoylphorbol-13-acetate. Overexpression inhibits NF-kappa-B-dependent gene expression in response to lipopolysaccharide at a level downstream of TRAF6 and upstream of IKBKB. NF-kappa-B inhibition is independent of TNFAIP3 binding.
-
分子量
- 35kD
-
基因ID
- 79931
-
UniProt
- Q96KP6
-
途径
- Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin
抗原
-