TJP3 抗体
Quick Overview for TJP3 抗体 (ABIN7232248)
抗原
See all TJP3 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- ZO3 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of ZO3 protein
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human ZO3 protein
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- TJP3 (Tight Junction Protein 3 (Zona Occludens 3) (TJP3))
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别名
- ZO3
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背景
- Rabbit Anti-ZO3 Polyclonal Antibody,Tight junction protein ZO-3, Tight junction protein 3, Zona occludens protein 3, Zonula occludens protein 3,The protein encoded by TJP3 is a member of the membrane-associated guanylate kinase-like (MAGUK) protein family which is characterized by members having multiple PDZ domains, a single SH3 domain, and a single guanylate kinase-like (GUK)-domain. In addition, members of the zonula occludens protein subfamily have an acidic domain, a basic arginine-rich region, and a proline-rich domain. The protein encoded by TJP3 plays a role in the linkage between the actin cytoskeleton and tight-junctions and also sequesters cyclin D1 at tight junctions during mitosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. TJP3 has a partial pseudogene on chromosome 1.,ZO3
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分子量
- observerd band 102kDa
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基因ID
- 27134
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UniProt
- O95049
抗原
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