THRB 抗体 (pSer142)
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北京 101111
Quick Overview for THRB 抗体 (pSer142) (ABIN7224696)
抗原
See all THRB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer142
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原理
- TRβ1 (phospho Ser142) Polyclonal Antibody
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特异性
- Phospho-TRβ1 (S142) Polyclonal Antibody detects endogenous levels of TRβ1 protein only when phosphorylated at S142.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human TRbeta1 Phospho-Ser142
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亚型
- IgG
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anti-Thyroid Hormone Receptor, beta (THRB) (AA 1-169) antibody
THRB 适用: 人 WB, IHC, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Hormone Receptor, beta (THRB) (AA 1-461) antibodyTHRB 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Hormone Receptor, beta (THRB) (AA 239-457) antibodyTHRB 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Hormone Receptor, beta (THRB) (AA 1-250) antibodyTHRB 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Hormone Receptor, beta (THRB) (AA 37-86) antibodyTHRB 适用: 人, 大鼠, 马, 犬, 豚鼠, 兔, 猴, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Hormone Receptor, beta (THRB) (N-Term) antibodyTHRB 适用: 人, 小鼠, 大鼠, 马, 豚鼠, Cow WB, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Hormone Receptor, beta (THRB) (N-Term) antibodyTHRB 适用: 人, 小鼠, 大鼠, 马, 犬, 兔, 绵羊 WB, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Hormone Receptor, beta (THRB) (AA 391-440) antibodyTHRB 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Hormone Receptor, beta (THRB) (N-Term) antibodyTHRB 适用: 人, 小鼠 WB, ELISA, IF, IP, FM 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Hormone Receptor, beta (THRB) (AA 23-55) antibodyTHRB 适用: 人 WB 宿主: 兔 Polyclonal RB54428 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- THRB (Thyroid Hormone Receptor, beta (THRB))
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别名
- TRbeta1
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背景
- Rabbit Anti-TRβ1 (phospho Ser142) Polyclonal Antibody,THRB, ERBA2, NR1A2, THR1, Thyroid hormone receptor beta, Nuclear receptor subfamily 1 group A member 2, c-erbA-2, c-erbA-beta,The protein encoded by THRB (thyroid hormone receptor beta) is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in THRB are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for THRB.,Thyroid hormone receptor beta
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分子量
- observerd band 45kDa
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基因ID
- 7068
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UniProt
- P10828
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途径
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Sensory Perception of Sound
抗原
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