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Thyroglobulin 抗体 (AA 2511-2560)

This 兔 多克隆 antibody specifically detects Thyroglobulin in ELISA 和 IHC (p). It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7231792
发货至: 中国
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Quick Overview for Thyroglobulin 抗体 (AA 2511-2560) (ABIN7231792)

抗原

See all Thyroglobulin (TG) 抗体
Thyroglobulin (TG)

适用

  • 186
  • 58
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  • 2
  • 1
人, 小鼠, 大鼠

宿主

  • 97
  • 90
  • 3
  • 2
  • 1
  • 1

克隆类型

  • 149
  • 45
多克隆

标记

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  • 5
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This Thyroglobulin antibody is un-conjugated

应用范围

  • 111
  • 63
  • 42
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  • 37
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  • 16
  • 16
  • 12
  • 6
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  • 1
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ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 8
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2511-2560

    原理

    Thyroglobulin Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of Thyroglobulin

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

    免疫原

    Synthesized peptide derived from part region of human Thyroglobulin protein at AA range: 2511-2560

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:50-1:200), ELISA (1:10000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    Thyroglobulin (TG)

    别名

    Thyroglobulin

    背景

    Rabbit Anti-Thyroglobulin Polyclonal Antibody,Thyroglobulin, Tg,Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in Thyroglobulin are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis. Diseases associated with TG include Thyroid Dyshormonogenesis 3 and Familial Thyroid Dyshormonogenesis.,Thyroglobulin

    基因ID

    7038

    UniProt

    P01266

    途径

    Thyroid Hormone Synthesis
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