TINF2 抗体 (AA 40-120)
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Quick Overview for TINF2 抗体 (AA 40-120) (ABIN7220998)
抗原
See all TINF2 (TIN2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 40-120
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原理
- TIN2 Polyclonal Antibody
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特异性
- TIN2 Polyclonal Antibody detects endogenous levels of TIN2 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human TIN2 at AA range: 40-120
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- TINF2 (TIN2) (TERF1 Interacting Nuclear Factor 2 (TIN2))
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别名
- TIN2
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背景
- Rabbit Anti-TIN2 Polyclonal Antibody,TINF2, TIN2, TERF1-interacting nuclear factor 2, TRF1-interacting nuclear protein 2,TINF2 encodes one of the proteins of the shelterin, or telosome, complex which protects telomeres by allowing the cell to distinguish between telomeres and regions of DNA damage. The TERF1 interacting nuclear factor 2 encoded by TINF2 is a critical part of shelterin, it interacts with the three DNA-binding proteins of the shelterin complex, and it is important for assembly of the complex. Mutations in this gene cause dyskeratosis congenita (DKC), an inherited bone marrow failure syndrome.,TERF1-interacting nuclear factor 2
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分子量
- observerd band 53kDa
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基因ID
- 26277
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UniProt
- Q9BSI4
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途径
- Cell Division Cycle, Telomere Maintenance, Regulation of Carbohydrate Metabolic Process
抗原
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