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TEAD2 抗体 (AA 40-120)

This anti-TEAD2 antibody is a 兔 多克隆 antibody detecting TEAD2 in ELISA, WB, IF 和 IHC (p). Suitable for 人 和 小鼠.
产品编号 ABIN7225436
发货至: 中国

Quick Overview for TEAD2 抗体 (AA 40-120) (ABIN7225436)

抗原

See all TEAD2 抗体
TEAD2 (TEA Domain Family Member 2 (TEAD2))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This TEAD2 antibody is un-conjugated

应用范围

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ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 40-120

    原理

    TEF-4 Polyclonal Antibody

    特异性

    TEF-4 Polyclonal Antibody detects endogenous levels of TEF-4 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the Internal region of human TEF-4 at AA range: 40-120

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    TEAD2 (TEA Domain Family Member 2 (TEAD2))

    别名

    TEF-4

    背景

    Rabbit Anti-TEF-4 Polyclonal Antibody,TEAD2, TEF4, Transcriptional enhancer factor TEF-4, TEA domain family member 2, TEAD-2,The Hippo pathway is an important evolutionarily conserved signaling pathway that controls organ size and tumor suppression by inhibiting cell proliferation and promoting apoptosis. An integral function of the Hippo pathway is to repress the activity of Yes-associated protein (YAP), a proposed oncogene whose activity is regulated by phosphorylation and subcellular localization. When the Hippo pathway is turned off, YAP is phosphorylated and translocates to the nucleus where it associates with various transcription factors including members of the transcriptional enhancer factor (TEF) family, also known as the TEA domain (TEAD) family (TEAD1-4). Although widely expressed in tissues, the TEAD family proteins have specific tissue and developmental distributions. YAP/TEAD complexes regulate the expression of genes involved in cell proliferation and apoptosis.,Transcriptional enhancer factor TEF-4

    基因ID

    8463

    UniProt

    Q15562

    途径

    Regulation of Lipid Metabolism by PPARalpha, Tube Formation
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