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TAPBP 抗体

This 兔 多克隆 anti-TAPBP antibody specifically detects TAPBP in WB 和 ELISA. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN7231882
发货至: 中国
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Quick Overview for TAPBP 抗体 (ABIN7231882)

抗原

See all TAPBP 抗体
TAPBP (TAP Binding Protein (Tapasin) (TAPBP))

适用

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人, 小鼠

宿主

  • 24
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克隆类型

  • 24
  • 2
多克隆

标记

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This TAPBP antibody is un-conjugated

应用范围

  • 24
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Western Blotting (WB), ELISA
  • 原理

    TPSN Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of TPSN protein

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

    免疫原

    Synthesized peptide derived from part region of human TPSN protein

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    TAPBP (TAP Binding Protein (Tapasin) (TAPBP))

    别名

    TPSN

    背景

    Rabbit Anti-TPSN Polyclonal Antibody,Tapasin, TPN, TPSN, NGS-17, TAP-associated protein, TAP-binding protein,TAPBP encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. TAPBP lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms.,TPSN

    分子量

    observerd band 49kDa

    基因ID

    6892

    UniProt

    O15533
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