TAO Kinase 1 (TAOK1) (AA 400-480) 抗体
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Quick Overview for TAO Kinase 1 (TAOK1) (AA 400-480) 抗体 (ABIN7223798)
抗原
See all TAO Kinase 1 (TAOK1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 400-480
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原理
- PSK2 Polyclonal Antibody
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特异性
- PSK2 Polyclonal Antibody detects endogenous levels of PSK2 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human PSK2 at AA range: 400-480
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- TAO Kinase 1 (TAOK1)
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别名
- PSK2
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背景
- Rabbit Anti-PSK2 Polyclonal Antibody,TAOK1, KIAA1361, MAP3K16, MARKK, Serine/threonine-protein kinase TAO1, Kinase from chicken homolog B, hKFC-B, MARK Kinase, MARKK, Prostate-derived sterile 20-like kinase 2, PSK-2, PSK2, Prostate-derived STE20-like kinase 2, Thousand and one,TAK1 is a mitogen-activated protein kinase kinase kinase that can be activated by TGF-β, bone morphogenetic protein and other cytokines including IL-1. In vivo activation of TAK1 requires association with TAK1 binding protein 1 (TAB1), which triggers phosphorylation of TAK1. Another adaptor protein, TAB2, links TAK1 with TRAF6 and mediates TAK1 activation upon IL-1 stimulation. Once activated, TAK1 phosphorylates MAPK kinases MKK4 and MKK3/6, which activate p38 MAPK and JNK, respectively. In addition, TAK1 activates the NF-κB pathway by interacting with TRAF6 and phosphorylating the NF-κB inducing kinase (NIK).,serine threonine-protein kinase TAO1
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分子量
- observerd band 120kDa
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基因ID
- 57551
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UniProt
- Q7L7X3
抗原
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