TNKS2 抗体 (AA 950-1030)
Quick Overview for TNKS2 抗体 (AA 950-1030) (ABIN7231854)
抗原
See all TNKS2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 950-1030
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原理
- TNKS2 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of TNKS2 protein
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human TNKS2 protein at AA range: 950-1030
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亚型
- IgG
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anti-Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase 2 (TNKS2) (AA 1-246) antibody
TNKS2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase 2 (TNKS2) (N-Term) antibodyTNKS2 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase 2 (TNKS2) (Internal Region) antibodyVerified TNKS2 适用: 人 WB 宿主: 山羊 Polyclonal unconjugated
anti-Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase 2 (TNKS2) (Internal Region) antibodyVerified TNKS2 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase 2 (TNKS2) (AA 1126-1156), (C-Term) antibodyTNKS2 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB14166 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- TNKS2 (Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase 2 (TNKS2))
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别名
- TNKS2
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背景
- Rabbit Anti-TNKS2 Polyclonal Antibody,Tankyrase-2, TANK2, ADP-ribosyltransferase diphtheria toxin-like 6, ARTD6, Poly [ADP-ribose] polymerase 5B, TNKS-2, TRF1-interacting ankyrin-related ADP-ribose polymerase 2, Tankyrase II, Tankyrase-like protein, Tankyrase-related protein,TNKS2 (Tankyrase 2) is a Protein Coding gene. Among its related pathways are phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex and HIV Life Cycle. GO annotations related to this gene include enzyme binding and NAD+ ADP-ribosyltransferase activity. An important paralog of this gene is TNKS. Poly-ADP-ribosyltransferase involved in various processes such as Wnt signaling pathway, telomere length and vesicle trafficking. Acts as an activator of the Wnt signaling pathway by mediating poly-ADP-ribosylation of AXIN1 and AXIN2, 2 key components of the beta-catenin destruction complex: poly-ADP-ribosylated target proteins are recognized by RNF146, which mediates their ubiquitination and subsequent degradation. Also mediates poly-ADP-ribosylation of BLZF1 and CASC3, followed by recruitment of RNF146 and subsequent ubiquitination. Mediates poly-ADP-ribosylation of TERF1, thereby contributing to the regulation of telomere length. May also regulate vesicle trafficking and modulate the subcellular distribution of SLC2A4/GLUT4-vesicles. Stimulates 26S proteasome activity.,TNKS2
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分子量
- observerd band 128kDa
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基因ID
- 80351
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UniProt
- Q9H2K2
抗原
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