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TCL1A 抗体 (AA 30-110)

The 兔 多克隆 anti-TCL1A antibody (ABIN7231744) specifically detects TCL1A in WB 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN7231744
发货至: 中国
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Quick Overview for TCL1A 抗体 (AA 30-110) (ABIN7231744)

抗原

See all TCL1A 抗体
TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))

适用

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宿主

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  • 1

克隆类型

  • 51
  • 34
多克隆

标记

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This TCL1A antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

    • 34
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    AA 30-110

    原理

    Tcl1 Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of Tcl1

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

    免疫原

    Synthesized peptide derived from part region of human Tcl1 protein at AA range: 30-110

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))

    别名

    Tcl1

    背景

    Rabbit Anti-Tcl1 Polyclonal Antibody,T-cell leukemia/lymphoma protein 1A, Oncogene TCL-1, Oncogene TCL1, Protein p14 TCL1,Overexpression of the TCL1 gene in humans has been implicated in the development of mature T cell leukemia, in which chromosomal rearrangements bring the TCL1 gene in close proximity to the T-cell antigen receptor (TCR)-alpha (MIM 186880) or TCR-beta (MIM 186930) regulatory elements (summarized by Virgilio et al. 1998 [PubMed 9520462]). In normal T cells TCL1 is expressed in CD4-/CD8- cells, but not in cells at later stages of differentiation. TCL1 functions as a coactivator of the cell survival kinase AKT (MIM 164730) TCL1A (T-Cell Leukemia/Lymphoma 1A) is a Protein Coding gene. Diseases associated with TCL1A include Precursor T-Cell Acute Lymphoblastic Leukemia and T-Cell Leukemia. Among its related pathways are PI3K-Akt signaling pathway and PI3K / Akt Signaling. An important paralog of TCL1A is MTCP1.,Tcl1

    分子量

    observerd band 13kDa

    基因ID

    8115

    UniProt

    P56279

    途径

    Stem Cell Maintenance
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