SNCA 抗体 (pTyr133)
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北京 101111
Quick Overview for SNCA 抗体 (pTyr133) (ABIN7224416)
抗原
See all SNCA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr133
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原理
- Synuclein-α (phospho Tyr133) Polyclonal Antibody
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特异性
- Phospho-Synuclein-α (Y133) Polyclonal Antibody detects endogenous levels of Synuclein-α protein only when phosphorylated at Y133.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human Synuclein-alpha Phospho-Tyr133
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亚型
- IgG
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anti-Synuclein, alpha (SNCA) (pSer129) antibody
SNCA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Synuclein, alpha (SNCA) (AA 61-140) antibodySNCA 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Synuclein, alpha (SNCA) (AA 40-140), (pSer129) antibodySNCA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Synuclein, alpha (SNCA) (AA 40-140), (pSer129) antibody (HRP)SNCA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal HRP
anti-Synuclein, alpha (SNCA) (AA 40-140), (pSer129) antibody (FITC)SNCA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal FITC
anti-Synuclein, alpha (SNCA) (AA 40-140), (pSer129) antibody (Biotin)SNCA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal Biotin
anti-Synuclein, alpha (SNCA) (AA 40-140), (pSer129) antibody (PE)SNCA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal PE
anti-Synuclein, alpha (SNCA) (AA 40-140), (pSer129) antibody (APC)SNCA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal APC
anti-Synuclein, alpha (SNCA) (AA 40-140), (pSer129) antibody (PerCP)SNCA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal PerCP
anti-Synuclein, alpha (SNCA) (AA 40-140), (pSer129) antibody (Atto 488)SNCA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal Atto 488
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- SNCA (Synuclein, alpha (SNCA))
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别名
- Synuclein-alpha
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背景
- Rabbit Anti-Synuclein-α (phospho Tyr133) Polyclonal Antibody,SNCA, NACP, PARK1, Alpha-synuclein, Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor, NACP,Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA (synuclein alpha) may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene.,Alpha-synuclein
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分子量
- observerd band 18kDa
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基因ID
- 6622
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UniProt
- P37840
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途径
- Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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