Synapsin III 抗体
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Quick Overview for Synapsin III 抗体 (ABIN7231616)
抗原
See all Synapsin III (SYN3) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- SYN3 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of SYN3 protein
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human SYN3 protein
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Synapsin III (SYN3)
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别名
- SYN3
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背景
- Rabbit Anti-SYN3 Polyclonal Antibody,Synapsin-3, Synapsin III,SYN3 is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. The protein encoded by SYN3 shares the synapsin family domain model, with domains A, C, and E exhibiting the highest degree of conservation. The protein contains a unique domain J, located between domains C and E. Based on this gene's localization to 22q12. , a possible schizophrenia susceptibility locus, and the established neurobiological roles of the synapsins, this family member may represent a candidate gene for schizophrenia. The TIMP3 gene is located within an intron of SYN3 and is transcribed in the opposite direction. Alternative splicing of SYN3 results in multiple splice variants that encode different isoforms.,SYN3
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分子量
- observerd band 63kDa
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基因ID
- 8224
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UniProt
- O14994
抗原
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