SYN2 抗体 (AA 370-450)
Our Local Distributor
北京 101111
Quick Overview for SYN2 抗体 (AA 370-450) (ABIN7231614)
抗原
See all SYN2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 370-450
-
原理
- Rabbit Anti-SYN2 Polyclonal Antibody
-
特异性
- The antibody detects endogenous levels of SYN2 protein
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
免疫原
- Synthesized peptide derived from part region of human SYN2 protein at AA range: 370-450
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
有效期
- 12 months
-
-
- SYN2 (Synapsin II (SYN2))
-
别名
- SYN2
-
背景
- Synapsin-2, Synapsin IISYN2 is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family encodes a neuron-specific phosphoprotein that selectively binds to small synaptic vesicles in the presynaptic nerve terminal. Polymorphisms in SYN2 are associated with abnormal presynaptic function and related neuronal disorders, including autism, epilepsy, bipolar disorder and schizophrenia. Alternative splicing of SYN2 results in multiple transcript variants. The tissue inhibitor of metalloproteinase 4 gene is located within an intron of SYN2 and is transcribed in the opposite direction.
-
分子量
- 64kD
-
基因ID
- 6854
-
UniProt
- Q92777
抗原
-