SUV39H2 抗体 (AA 80-160)
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Quick Overview for SUV39H2 抗体 (AA 80-160) (ABIN7215544)
抗原
See all SUV39H2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 80-160
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原理
- KMT1B Polyclonal Antibody
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特异性
- KMT1B Polyclonal Antibody detects endogenous levels of KMT1B protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human KMT1B at AA range: 80-160
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亚型
- IgG
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anti-Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2) antibody
SUV39H2 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2) (AA 93-122) antibodySUV39H2 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2) (AA 360-390) antibodySUV39H2 适用: 人, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2) (AA 201-410) antibodySUV39H2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2) (AA 93-122), (N-Term) antibodySUV39H2 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB02737 unconjugated
anti-Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2) (AA 141-350) antibodySUV39H2 适用: 人 WB, ChIP, IF 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2) (Internal Region) antibodySUV39H2 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2) (Internal Region) antibodySUV39H2 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2) (AA 360-390), (C-Term) antibodySUV39H2 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB02739 unconjugated
anti-Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2) antibodySUV39H2 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB3835 unconjugated Recombinant Antibody
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- SUV39H2 (Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2))
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别名
- KMT1B
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背景
- Rabbit Anti-KMT1B Polyclonal Antibody,SUV39H2, KMT1B, Histone-lysine N-methyltransferase SUV39H2, Histone H3-K9 methyltransferase 2, H3-K9-HMTase 2, Lysine N-methyltransferase 1B, Suppressor of variegation 3-9 homolog 2, Su(var)3-9 homolog 2,Histone-lysine N-methyltransferase SUV39H2 is a Histone methyltransferase that specifically trimethylates Lys-9 of histone H3 using monomethylated H3 Lys-9 as substrate. H3 Lys-9 trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin at pericentric and telomere regions. H3 Lys-9 trimethylation is also required to direct DNA methylation at pericentric repeats. SUV39H1 is targeted to histone H3 via its interaction with RB1 and is involved in many processes, such as cell cycle regulation, transcriptional repression and regulation of telomere length. May participate in regulation of higher-order chromatin organization during spermatogenesis. Recruited by the large PER complex to the E-box elements of the circadian target genes such as PER2 itself or PER1, contributes to the conversion of local chromatin to a heterochromatin-like repressive state through H3 Lys-9 trimethylation. Among its related pathways are Lysine degradation and Chromatin organization. Gene Ontology (GO) annotations related to this gene include chromatin binding and transcription regulatory region sequence-specific DNA binding. An important paralog of this gene is EHMT1.,Histone-lysine N-methyltransferase SUV39H2
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分子量
- observerd band 46kDa
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基因ID
- 79723
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UniProt
- Q9H5I1
抗原
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