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SOCS3 抗体 (AA 20-70)

This 兔 多克隆 anti-SOCS3 antibody specifically detects SOCS3 in ELISA 和 IHC (p). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7231436
发货至: 中国
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Quick Overview for SOCS3 抗体 (AA 20-70) (ABIN7231436)

抗原

See all SOCS3 抗体
SOCS3 (Suppressor of Cytokine Signaling 3 (SOCS3))

适用

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人, 小鼠, 大鼠

宿主

  • 55
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克隆类型

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多克隆

标记

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This SOCS3 antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 20-70

    原理

    SOCS-3 Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of SOCS-3

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

    免疫原

    Synthesized peptide derived from part region of human SOCS-3 protein at AA range: 20-70

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:50-1:200), ELISA (1:10000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    SOCS3 (Suppressor of Cytokine Signaling 3 (SOCS3))

    别名

    SOCS-3

    背景

    Rabbit Anti-SOCS-3 Polyclonal Antibody,Suppressor of cytokine signaling 3, SOCS-3, Cytokine-inducible SH2 protein 3, CIS-3, STAT-induced STAT inhibitor 3, SSI-3,SOCS3 encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of SOCS3 is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by SOCS3 can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of SOCS3 suggested the roles of SOCS3 in the negative regulation of fetal liver hematopoiesis, and placental development. SOCS3 (Suppressor Of Cytokine Signaling 3) is a Protein Coding gene. Diseases associated with SOCS3 include Overnutrition and Atopic Dermatitis. Among its related pathways are Type II interferon signaling (IFNG) and Adipocytokine signaling pathway.,SOCS-3

    基因ID

    9021

    UniProt

    O14543

    途径

    JAK/STAT Signaling, Response to Growth Hormone Stimulus, Hepatitis C
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