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SOCS2 抗体 (Internal Region)

This 兔 多克隆 anti-SOCS2 antibody specifically detects SOCS2 in WB 和 ELISA. The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN7217074
发货至: 中国
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Quick Overview for SOCS2 抗体 (Internal Region) (ABIN7217074)

抗原

See all SOCS2 抗体
SOCS2 (Suppressor of Cytokine Signaling 2 (SOCS2))

适用

  • 53
  • 18
  • 9
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
人, 大鼠, 小鼠

宿主

  • 53
  • 3

克隆类型

  • 34
  • 22
多克隆

标记

  • 26
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
This SOCS2 antibody is un-conjugated

应用范围

  • 29
  • 17
  • 14
  • 12
  • 12
  • 7
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region

    原理

    SOCS-2 Polyclonal Antibody

    特异性

    SOCS-2 Polyclonal Antibody detects endogenous levels of SOCS-2 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the Internal region of human SOCS-2

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    SOCS2 (Suppressor of Cytokine Signaling 2 (SOCS2))

    别名

    SOCS-2

    背景

    Rabbit Anti-SOCS-2 Polyclonal Antibody,SOCS2, CIS2, SSI2, STATI2, Suppressor of cytokine signaling 2, SOCS-2, Cytokine-inducible SH2 protein 2, CIS-2, STAT-induced STAT inhibitor 2, SSI-2,SOCS2 encodes a member of the suppressor of cytokine signaling (SOCS) family. SOCS family members are cytokine-inducible negative regulators of cytokine receptor signaling via the Janus kinase/signal transducer and activation of transcription pathway (the JAK/STAT pathway). SOCS family proteins interact with major molecules of signaling complexes to block further signal transduction, in part, by proteasomal depletion of receptors or signal-transducing proteins via ubiquitination. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10, interferon (IFN)-gamma and by cytokine receptors such as growth horomone receptor. Suppressor of cytokine signaling 2 encoded by SOCS2 interacts with the cytoplasmic domain of insulin-like growth factor-1 receptor (IGF1R) and is thought to be involved in the regulation of IGF1R mediated cell signaling. This gene has pseudogenes on chromosomes 20 and 22. Alternative splicing results in multiple transcript variants.,Suppressor of cytokine signaling 2

    分子量

    observerd band 22kDa

    基因ID

    8835

    UniProt

    O14508

    途径

    JAK/STAT Signaling, Response to Growth Hormone Stimulus
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