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SMC1B 抗体 (AA 110-190)

The 兔 多克隆 anti-SMC1B antibody (ABIN7231408) specifically detects SMC1B in WB 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN7231408
发货至: 中国
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Quick Overview for SMC1B 抗体 (AA 110-190) (ABIN7231408)

抗原

See all SMC1B 抗体
SMC1B (Structural Maintenance of Chromosomes 1B (SMC1B))

适用

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宿主

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克隆类型

  • 19
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多克隆

标记

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This SMC1B antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 110-190

    原理

    SMC1B Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of SMC1B protein

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

    免疫原

    Synthesized peptide derived from part region of human SMC1B protein at AA range: 110-190

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    SMC1B (Structural Maintenance of Chromosomes 1B (SMC1B))

    别名

    SMC1B

    背景

    Rabbit Anti-SMC1B Polyclonal Antibody,Structural maintenance of chromosomes protein 1B, SMC protein 1B, SMC-1-beta, SMC-1B,SMC1B (Structural Maintenance Of Chromosomes 1B) is a Protein Coding gene. Among its related pathways are Meiosis and Oocyte meiosis. An important paralog of this gene is SMC1A. Meiosis-specific component of cohesin complex. Required for the maintenance of meiotic cohesion, but not, or only to a minor extent, for its establishment. Contributes to axial element (AE) formation and the organization of chromatin loops along the AE. Plays a key role in synapsis, recombination and chromosome movements. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I (By similarity).,SMC1B

    分子量

    observerd band 135kDa

    基因ID

    27127

    UniProt

    Q8NDV3
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