SMC1B 抗体 (AA 110-190)
Quick Overview for SMC1B 抗体 (AA 110-190) (ABIN7231408)
抗原
See all SMC1B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 110-190
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原理
- SMC1B Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of SMC1B protein
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human SMC1B protein at AA range: 110-190
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- SMC1B (Structural Maintenance of Chromosomes 1B (SMC1B))
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别名
- SMC1B
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背景
- Rabbit Anti-SMC1B Polyclonal Antibody,Structural maintenance of chromosomes protein 1B, SMC protein 1B, SMC-1-beta, SMC-1B,SMC1B (Structural Maintenance Of Chromosomes 1B) is a Protein Coding gene. Among its related pathways are Meiosis and Oocyte meiosis. An important paralog of this gene is SMC1A. Meiosis-specific component of cohesin complex. Required for the maintenance of meiotic cohesion, but not, or only to a minor extent, for its establishment. Contributes to axial element (AE) formation and the organization of chromatin loops along the AE. Plays a key role in synapsis, recombination and chromosome movements. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I (By similarity).,SMC1B
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分子量
- observerd band 135kDa
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基因ID
- 27127
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UniProt
- Q8NDV3
抗原
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