SOAT1 抗体
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北京 101111
Quick Overview for SOAT1 抗体 (ABIN7231432)
抗原
See all SOAT1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Rabbit Anti-SOAT1 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of SOAT1 protein
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from part region of human SOAT1 protein
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- SOAT1 (Sterol O-Acyltransferase 1 (SOAT1))
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别名
- SOAT1
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背景
- Sterol O-acyltransferase 1, Acyl-coenzyme A:cholesterol acyltransferase 1, ACAT-1, Cholesterol acyltransferase 1SOAT1 (Sterol O-Acyltransferase 1) is a Protein Coding gene. Diseases associated with SOAT1 include Chronic Leukemia and Homozygous Familial Hypercholesterolemia. Among its related pathways are Statin Pathway and Metabolism. The protein encoded by SOAT1 belongs to the acyltransferase family. It is located in the endoplasmic reticulum, and catalyzes the formation of fatty acid-cholesterol esters. SOAT1 has been implicated in the formation of beta-amyloid and atherosclerotic plaques by controlling the equilibrium between free cholesterol and cytoplasmic cholesteryl esters. Alternatively spliced transcript variants have been found for SOAT1.
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分子量
- 60kD
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基因ID
- 6646
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UniProt
- P35610
抗原
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