Stanniocalcin 2 抗体 (AA 170-250)
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Quick Overview for Stanniocalcin 2 抗体 (AA 170-250) (ABIN7231560)
抗原
See all Stanniocalcin 2 (STC2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 170-250
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原理
- STC2 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of STC2 protein
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human STC2 protein at AA range: 170-250
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Stanniocalcin 2 (STC2)
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别名
- STC2
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背景
- Rabbit Anti-STC2 Polyclonal Antibody,Stanniocalcin-related protein, STC-related protein, STCRP,STC2 encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression of STC2 is induced by estrogen and altered in some breast cancers.,STC2
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分子量
- observerd band 33kDa
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基因ID
- 8614
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UniProt
- O76061
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途径
- Hormone Activity, ER-Nucleus Signaling, SARS-CoV-2 Protein Interactome
抗原
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