HTR2A 抗体 (AA 400-480)
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Quick Overview for HTR2A 抗体 (AA 400-480) (ABIN7221614)
抗原
See all HTR2A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 400-480
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原理
- Rabbit Anti-SR-2A Polyclonal Antibody
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特异性
- SR-2A Polyclonal Antibody detects endogenous levels of SR-2A protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from the C-terminal region of human SR-2A at AA range: 400-480
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:5000,Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- HTR2A (5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A))
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别名
- SR-2A
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背景
- HTR2A, HTR2, 5-hydroxytryptamine receptor 2A, 5-HT-2, 5-HT-2A, Serotonin receptor 2AHTR2A encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in HTR2A are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene.
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基因ID
- 3356
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UniProt
- P28223
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途径
- JAK/STAT Signaling, Inositol Metabolic Process, Regulation of Carbohydrate Metabolic Process
抗原
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