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SPHK2 抗体 (pThr614)

This 兔 多克隆 antibody specifically detects SPHK2 in WB, IHC, ELISA 和 IF. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7223678
发货至: 中国
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Quick Overview for SPHK2 抗体 (pThr614) (ABIN7223678)

抗原

See all SPHK2 抗体
SPHK2 (Sphingosine Kinase 2 (SPHK2))

适用

人, 小鼠, 大鼠

宿主

  • 55
  • 2

克隆类型

  • 57
多克隆

标记

  • 40
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SPHK2 antibody is un-conjugated

应用范围

  • 44
  • 32
  • 30
  • 6
  • 5
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 10
    • 9
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr614

    原理

    Rabbit Anti-SphK2 (phospho Thr614) Polyclonal Antibody

    特异性

    Phospho-SphK2 (T614) Polyclonal Antibody detects endogenous levels of SphK2 protein only when phosphorylated at T614.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from human SphK2 Phospho-Thr614

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:100-1:300,ELISA 1:5000,IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    SPHK2 (Sphingosine Kinase 2 (SPHK2))

    别名

    SphK2

    背景

    SPHK2, Sphingosine kinase 2, SK 2, SPK 2SPHK2 (sphingosine kinase 2) encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate. Sphingosine 1-phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for SPHK2.

    基因ID

    56848

    UniProt

    Q9NRA0

    途径

    VEGF Signaling
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