SPHK1 抗体 (AA 160-240)
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Quick Overview for SPHK1 抗体 (AA 160-240) (ABIN7231496)
抗原
See all SPHK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 160-240
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原理
- SPHK1 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of SPHK1 protein
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human SPHK1 protein at AA range: 160-240
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- SPHK1 (Sphingosine Kinase 1 (SPHK1))
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别名
- SPHK1
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背景
- Rabbit Anti-SPHK1 Polyclonal Antibody,Sphingosine kinase 1, SK 1, SPK 1, SPHK1, SPK,The protein encoded by SPHK1 catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Alternatively spliced transcript variants encoding different isoforms have been found for SPHK1.,SPHK1
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分子量
- observerd band 42kDa
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基因ID
- 8877
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UniProt
- Q9NYA1
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途径
- VEGF Signaling
抗原
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