SPAG8 抗体
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北京 101111
Quick Overview for SPAG8 抗体 (ABIN7231482)
抗原
See all SPAG8 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- SPAG8 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of SPAG8 protein
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human SPAG8 protein
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亚型
- IgG
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anti-Sperm Associated Antigen 8 (SPAG8) (AA 1-501) antibody
SPAG8 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 2F12 unconjugated
anti-Sperm Associated Antigen 8 (SPAG8) (AA 1-501) antibodySPAG8 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Sperm Associated Antigen 8 (SPAG8) (AA 342-426) antibodySPAG8 适用: 人 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Sperm Associated Antigen 8 (SPAG8) (AA 220-420) antibodySPAG8 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sperm Associated Antigen 8 (SPAG8) (AA 236-409) antibodySPAG8 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Sperm Associated Antigen 8 (SPAG8) (AA 396-445) antibodySPAG8 适用: 人, 小鼠, 大鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Sperm Associated Antigen 8 (SPAG8) (AA 143-192) antibodySPAG8 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Sperm Associated Antigen 8 (SPAG8) (Middle Region) antibodySPAG8 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Sperm Associated Antigen 8 (SPAG8) (N-Term) antibodySPAG8 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Sperm Associated Antigen 8 (SPAG8) (Middle Region) antibodySPAG8 适用: 人, 小鼠, 大鼠, 兔, Cow, 犬, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- SPAG8 (Sperm Associated Antigen 8 (SPAG8))
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别名
- SPAG8
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背景
- Rabbit Anti-SPAG8 Polyclonal Antibody,Sperm-associated antigen 8, HSD-1, Sperm membrane protein 1, SMP-1, Sperm membrane protein BS-84,The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. Sperm Associated Antigen 8 encoded by SPAG8 is recognized by sperm agglutinating antibodies from an infertile woman. Sperm Associated Antigen 8 is localized in germ cells of the testis at all stages of spermatogenesis and is localized to the acrosomal region of mature spermatozoa. Sperm Associated Antigen 8 interacts with ACT (activator of CREM in testis) and may play a role in CREM (cAMP response element modulator) -ACT-mediated gene transcription during spermatogenesis. Sperm Associated Antigen 8 may also play a role in spermatogenesis by regulating microtubule formation and cell division. Alternatively spliced variants that encode different protein isoforms have been described but the full-length sequences of only two have been determined.,SPAG8
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分子量
- observerd band 46kDa
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基因ID
- 26206
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UniProt
- Q99932
抗原
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