SPTBN1 抗体 (AA 620-700)
Quick Overview for SPTBN1 抗体 (AA 620-700) (ABIN7224444)
抗原
See all SPTBN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 620-700
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原理
- Spectrin β II Polyclonal Antibody
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特异性
- Spectrin β II Polyclonal Antibody detects endogenous levels of Spectrin β II protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human Spectrin beta II at AA range: 620-700
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- SPTBN1 (Spectrin Beta, Non-Erythrocytic 1 (SPTBN1))
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别名
- Spectrin beta II
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背景
- Rabbit Anti-Spectrin β II Polyclonal Antibody,SPTBN1, SPTB2, Spectrin beta chain, non-erythrocytic 1, Beta-II spectrin, Fodrin beta chain, Spectrin, non-erythroid beta chain 1,Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is composed of two antiparallel dimers of alpha- and beta- subunits. SPTBN1 (spectrin beta, non-erythrocytic 1) is one member of a family of beta-spectrin genes. The encoded protein contains an N-terminal actin-binding domain, and 17 spectrin repeats which are involved in dimer formation. Multiple transcript variants encoding different isoforms have been found for SPTBN1.,Spectrin beta chain non-erythrocytic 1
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分子量
- observerd band 275kDa
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基因ID
- 6711
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UniProt
- Q01082
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途径
- Regulation of Actin Filament Polymerization, Protein targeting to Nucleus
抗原
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