SPTAN1 抗体 (Cleaved-Asp1185)
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Quick Overview for SPTAN1 抗体 (Cleaved-Asp1185) (ABIN7212504)
抗原
See all SPTAN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1110-1190, Cleaved-Asp1185
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原理
- Cleaved-Spectrin α II (D1185) Polyclonal Antibody
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特异性
- Cleaved-Spectrin α II (D1185) Polyclonal Antibody detects endogenous levels of fragment of activated Spectrin α II protein resulting from cleavage adjacent to D1185.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human Spectrin alpha II at AA range: 1110-1190
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亚型
- IgG
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anti-Spectrin alpha Chain, Brain (SPTAN1) (AA 950-1130) antibody
SPTAN1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Spectrin alpha Chain, Brain (SPTAN1) (AA 2071-2269) antibodySPTAN1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Spectrin alpha Chain, Brain (SPTAN1) antibodySPTAN1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Spectrin alpha Chain, Brain (SPTAN1) (AA 1573-1742) antibodySPTAN1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Spectrin alpha Chain, Brain (SPTAN1) antibodySPTAN1 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Spectrin alpha Chain, Brain (SPTAN1) antibodySPTAN1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Spectrin alpha Chain, Brain (SPTAN1) antibodyKD Validated SPTAN1 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 24GB13380 unconjugated
anti-Spectrin alpha Chain, Brain (SPTAN1) (AA 2351-2475) antibodySPTAN1 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal SPTAN1-3351 unconjugated
anti-Spectrin alpha Chain, Brain (SPTAN1) (AA 289-408) antibodySPTAN1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Spectrin alpha Chain, Brain (SPTAN1) (AA 977-991) antibodySPTAN1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal RB50708 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- SPTAN1 (Spectrin alpha Chain, Brain (SPTAN1))
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别名
- Spectrin alpha II
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背景
- Rabbit Anti-Cleaved-Spectrin α II (D1185) Polyclonal Antibody,SPTAN1, NEAS, SPTA2, Spectrin alpha chain, non-erythrocytic 1, Alpha-II spectrin, Fodrin alpha chain, Spectrin, non-erythroid alpha subunit,Spectrins are a family of filamentous cytoskeletal proteins that function as essential scaffold proteins that stabilize the plasma membrane and organize intracellular organelles. Spectrins are composed of alpha and beta dimers that associate to form tetramers linked in a head-to-head arrangement. SPTAN1 encodes an alpha spectrin that is specifically expressed in nonerythrocytic cells. Spectrin alpha chain non-erythrocytic 1 has been implicated in other cellular functions including DNA repair and cell cycle regulation. Mutations in SPTAN1 are the cause of early infantile epileptic encephalopathy-5. Alternate splicing results in multiple transcript variants.,Spectrin alpha chain non-erythrocytic 1
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分子量
- observerd band 137kDa
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基因ID
- 6709
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UniProt
- Q13813
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途径
- Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization
抗原
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