SP100 抗体 (AA 250-330)
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北京 101111
Quick Overview for SP100 抗体 (AA 250-330) (ABIN7224440)
抗原
See all SP100 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 250-330
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原理
- SP-100 Polyclonal Antibody
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特异性
- SP-100 Polyclonal Antibody detects endogenous levels of SP-100 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human SP-100 at AA range: 250-330
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- SP100 (SP100 Nuclear Antigen (SP100))
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别名
- SP-100
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背景
- Rabbit Anti-SP-100 Polyclonal Antibody,SP100, Nuclear autoantigen Sp-100, Lysp100b, Nuclear dot-associated Sp100 protein, Speckled 100 kDa,SP100 (SP100 nuclear antigen) encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia)-SP100 nuclear bodies. PML and SP100 are covalently modified by the SUMO-1 modifier, which is considered crucial to nuclear body interactions. The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis, immunity, and gene regulation. Alternatively spliced variants have been identified for SP100, one of which encodes a high-mobility group protein.,Nuclear autoantigen Sp-100
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分子量
- observerd band 100kDa
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基因ID
- 6672
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UniProt
- P23497
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途径
- Retinoic Acid Receptor Signaling Pathway
抗原
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