SLC22A5 抗体 (AA 270-350)
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Quick Overview for SLC22A5 抗体 (AA 270-350) (ABIN7224390)
抗原
See all SLC22A5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 270-350
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原理
- OCTN2 Polyclonal Antibody
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特异性
- OCTN2 Polyclonal Antibody detects endogenous levels of OCTN2 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human OCTN2 at AA range: 270-350
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- SLC22A5 (Solute Carrier Family 22 Member 5 (SLC22A5))
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别名
- OCTN2
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背景
- Rabbit Anti-OCTN2 Polyclonal Antibody,SLC22A5, OCTN2, Solute carrier family 22 member 5, High-affinity sodium-dependent carnitine cotransporter, Organic cation/carnitine transporter 2,Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. The encoded protein is a plasma integral membrane protein which functions both as an organic cation transporter and as a sodium-dependent high affinity carnitine transporter. The encoded protein is involved in the active cellular uptake of carnitine. Mutations in SLC22A5 (solute carrier family 22 member 5)are the cause of systemic primary carnitine deficiency (CDSP), an autosomal recessive disorder manifested early in life by hypoketotic hypoglycemia and acute metabolic decompensation, and later in life by skeletal myopathy or cardiomyopathy. Alternative splicing of SLC22A5 results in multiple transcript variants.,Solute carrier family 22 member 5
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分子量
- observerd band 65kDa
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基因ID
- 6584
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UniProt
- O76082
抗原
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