SMAD1 抗体
Quick Overview for SMAD1 抗体 (ABIN7218228)
抗原
See all SMAD1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Smad1 Polyclonal Antibody
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特异性
- Smad1 Polyclonal Antibody detects endogenous levels of Smad1 protein only when non-phosphorylation at S214.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human Smad1 around the non-phosphorylation site of S214
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亚型
- IgG
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anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) (AA 20-240) antibody
SMAD1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) (AA 1-465) antibodySMAD1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2E9 unconjugated
anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) (AA 1-465) antibodySMAD1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2A1 unconjugated
anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) (AA 1-110) antibodySMAD1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1D3 unconjugated
anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) (AA 202-335) antibodySMAD1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) (pSer187) antibodySMAD1 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) (AA 163-196) antibodySMAD1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) (AA 20-330) antibodySMAD1 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Monoclonal 1356CT119-18-55 unconjugated
anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) (AA 163-196) antibodySMAD1 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB43846 unconjugated
anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) (pSer465) antibodySMAD1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- SMAD1 (SMAD, Mothers Against DPP Homolog 1 (SMAD1))
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别名
- Smad1
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背景
- Rabbit Anti-Smad1 Polyclonal Antibody,SMAD1, BSP1, MADH1, MADR1, Mothers against decapentaplegic homolog 1, MAD homolog 1, Mothers against DPP homolog 1, JV4-1, Mad-related protein 1, SMAD family member 1, SMAD 1, Smad1, hSMAD1, Transforming growth factor-beta-signaling protein 1, BSP-1,SMAD family member 1 encoded by SMAD1 belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed.,Mothers against decapentaplegic homolog 1
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分子量
- observerd band 52kDa
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基因ID
- 4086
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UniProt
- Q15797
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途径
- Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
抗原
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